Transcribed Ultraconserved Regions in Cancer

Transcribed ultraconserved regions are putative lncRNA molecules that are transcribed from DNA that is 100% conserved in human, mouse, and rat genomes.This is notable, as lncRNAs are typically poorly conserved.TUCRs Gloves remain very understudied in many diseases, including cancer.In this review, Whips we summarize the current literature on TUCRs in cancer with respect to expression deregulation, functional roles, mechanisms of action, and clinical perspectives.